Ammonia in the Brain
Neurophotonic Therapy is trademarked, and its scientific foundations were originally researched, developed, and reported by Dr. David A. Jernigan, D.C. This is copywritten material and should be referenced accordingly.
Localized Ammonia Production by Lyme Spirochetes
By David A. Jernigan, D.C.
Using "Direct Resonance Testing" to test for the presence of ammonia in the brain and other tissues of 50 chronic Lyme patients; all patients were positive for ammonia over some area of their brain. Several other doctors have confirmed this finding. A direct resonance test functions based upon the fact that every bend, rotation, or atomic bond of a given molecular structure, such as NH3, has a certain resonant frequency. When two substances similar molecular frequency come in close proximity to each other they will tend to vibrate "sympathetically" through harmonic resonance.
This is a simple test that can help screen Lyme patients for the presence of ammonia in various regions of the brain. I have found virtually every Lyme patient tests positive to having ammonia in specific locations of the brain.
It is possible that at least one of the potentially many types of neurotoxins produced by Borrelia burg. is ammonia. I postulate that the various and many neurological symptoms seen in LD are the result of small amounts of ammonia affecting localized areas of the brain, as opposed to the brain swelling due to liver problems, which affects the astrocytes of the entire brain.
The way I see it is that Bb release NH3, which is converted to glutamine, by way of the glutamine synthetase pathways, leading to localized swelling of astrocytes. Depending upon the severity of infection and tissue environmental issues, including pH, temperature, oxygen levels, emotional state… the amount of ammonia could cause variable and cyclical worsening of symptoms.
Localized astrocyte swelling would be aggravated by changes in barometric pressure, due to the fact that any intracellular swelling is going to swell more when there is less atmospheric pressure on it, as in the case of falling barometric pressure before a storm, thereby causing a worsening of symptoms. Weather-related worsening as seen with moon phases and prior to storms are a common complaint in LD.
All of the ammonia-related pathological changes predispose these individuals to cerebral allergies, due to alterations in the blood brain barrier, subsequently allowing larger molecules to pass through to the brain. Neurotransmitter receptors and function is impaired and possibly the most common symptom – altered brain energy metabolism leading to cognitive brain dysfunctions, the total fatigue of the mind when forced to read, talk, or think for extended periods.
The Bb in joints and musculoskeletal tissues may be creating symptoms due to the conversion of NH3 to nitric oxide (NO), which is well documented as causing multiple pathological processes, including sepsis, hyperactive inflammatory processes, and joint pain. Direct resonance testing has revealed that the liver and heart are often testing positive to accumulations of NH3, which is not being converted into urea or nitric oxide.
Lyme-ammonia encephalopathy may explain why Cholestyramine, an ammonia sponge of sorts, provides some relief in LD. However, in that ammonia is only a byproduct of Bb, we can hope for symptom relief only, by using ammonia-clearing products. This is perfectly fine since many LD patients cannot tolerate the herx of the increased toxic dump experienced when Bb are killed.
A possible treatment would follow that of Trypanosoma gambiense, another producer of ammonia in the brain. Eflornithine (Difluoromethyl-ornithine- DFMO) was considered a “Resurrection Drug” although it was subsequently dropped from production due to poor economic value, in that most of the people needing it were poor Africans suffering from Sleeping Sickness, which is not too far removed from the fatigue and sleep disorders of chronic LD.
Since DFMO is no longer on the market, I have been using several supplements. L-Ornithine, a simple amino-acid. Ornithine degradation provides glutamate for ammonia detoxification into urea, which can then be excreted via the kidneys. The best ammonia-clearing product I have been able to come up with is a combination of chlorella, molybdenum, beta-sitosterol, and silphium laciniatum. I have researched and developed two novel use botanicals, silphium laciniatum and Pale-Spike Lobelia Extract. The silphium is used in a frequency-matched formulas called the “Neuro Antitox Formulas,” which have been targeted to the specific areas of the body being most affected by the neurotoxins. The Pale-Spike Lobelia extract is a single ingredient that is highly synergistic with the NeuroAntitox Formulas. The changes we have seen in LD patients via FACT testing (Functional Acuity Contrast Test), sometimes called a Visual Contrast Sensitivity Test, are remarkable. The FACT test is admissible in a court of law to verify the level of neurotoxin interference in brain tissue. It takes only 5-10 minutes and can be performed by the doctor’s staff. With the NeuroAntitox we have been able to demonstrate consistent improvement of FACT scores, within a week of oral supplementation. Improvement continues almost universally on repeat weekly testing. Symptomatic relief follows the detoxification of neurotoxins, such as ammonia and heavy metals. It is suspicioned by this author, that there is a life-sustaining synergy between the ammonia and the Lyme spirochetes. This suspicion is due to the fact of the more rapid than usual clearing of Lyme spirochetes from detection via resonance testing.
Once the ammonia levels are cleared and the Bb microbes are reduced, supplemental L-arginine can be taken in the morning to “wake up” or energize the brain. (L-arginine should not be taken in the presence of ammonia. Research reveals that NH3 + arginine and manganese increases nitric oxide (NO) up to 53% in astrocytes, leading to increased brain swelling). Armed with this knowledge, health care professionals would be wise to instigate a protein poor diet for Lyme patients, during treatment to minimize aggravations from arginine.
The “Direct Resonance Testing,” molecular vibration phenomenon is not theory. Complex molecules may contain thousands or even millions of atoms. How they bind together creates an electromagnetic "signature," which is extremely precise and specific to the type of molecule. It is this molecular resonance that enables a doctor to perform a simple, quick test to determine the presence of ammonia in the brain or any other tissue. The same can be done as a quick screen for Bb, using a fixed Bb specimen.
To perform a direct resonance test the doctor will need a vial of pure ammonia. A muscle strength challenge should be performed to identify a strong muscle, preferably using the deltoid muscle with the patient's thumb pointing towards the feet. The muscle should "lock" immediately when challenged, without being spongy. Once a good strong muscle has been identified, hold the vial of ammonia over various areas of the brain, testing to see if the previously strong muscle goes weak when the ammonia is held over any area. Due to the temporary neuromuscular interference caused by the harmonic resonance of ammonia in the vial with the ammonia present in the brain, the strong muscle will go weak. The best effective treatment can be identified by adding the corrective substance, be it the liquid botanical supplement, Pale-Spike Lobelia, the encapsulated NeuroAntitox Formulas (Jernigan Nutraceuticals) or prescription Cholestyramine. To determine the best corrective substance hold the vial of ammonia and a corrective substance over the same spot where the strong muscle went weak. If you have found the proper corrective substance the former weak muscle test now will go strong.
In summary, I know of no other testing method that provides such immediate confirmation of localized NH3 as the Direct Resonance Test. Localized ammonia is present in virtually every chronic LD patient, either from the spirochete or other indirect mechanism. We have found ammonia wherever Lyme spirochetes reside in the body, but primarily over the liver, heart, teeth, and cranium.
I must say that all of our LD patients are either on Borrelogen or Microbojen or both while taking the NeuroAntitox Formula and Pale-Spike Lobelia Extract (not to be confused with Lobelia inflata), as well as a strong systemic proteolytic enzyme supplement, such as Wobenzym-N, Nutrazyme, or Vitalzyme. Therefore, to reproduce our good results may require one to follow this type of protocol. More on the Lyme toxin issue can be read in our new book, “Beating Lyme Disease; Using Alternative Medicine and God-Designed Living.” This is a hardback book with 410 pages, and can be ordered by calling toll free 877.456.8872 or through amazon.com.
Your thoughts and comments are appreciated.
(http://www.jernigannutraceuticals.com)
