This article is great for understanding why Lyme symptoms worsen at high oestrogen points of our menstrual cycle, and it's not because our bodies are doing more bug killing, but because oestrogen makes the gut lining more permeable allowing endotoxin to enter the blood stream, it also reduces oxygen to the digestive tract which encourages bacterial overgrowth and oestrogen in excess can put us into a state of shock (or herx). A really fascinating read for anyone who has ever wondered why their symptoms worsen at ovulation and pre-mesntrually
.http://www.dannyroddy.com/main/2012/5/14/estrogen-the-shit-show-hormone.html