The researchers found that neuroinflammation is higher in CFS patients than in healthy people. Furthermore, they also found that inflammation in certain areas of the brain – the cingulate cortex, hippocampus, amygdala, thalamus, midbrain and pons – was elevated in a way that correlated with the symptoms. For instance, patients who reported impaired cognition tended to demonstrate neuroinflammation in the amygdala, which is known to be involved in cognition. This provides evidence of the association between neuroinflammation and the symptoms experienced by patients with CFS.
