"Brain SPECT scans are abnormal in most patients with chronic Lyme disease, and these scans can be used to provide objective evidence in support of the clinical diagnosis.

"Brain SPECT scans are abnormal in most patients with chronic Lyme disease, and these scans can be used to provide objective evidence in support of the clinical diagnosis. The use of certain antibiotic regimens seems to provide improvement in both clinical status and SPECT scans".
http://www.ncbi.nlm.nih.gov/pubmed/22889796

SPECT brain imaging in chronic Lyme disease. - PubMed - NCBI

Clin Nucl Med. 2012 Sep;37(9):e219-22. doi: 10.1097/RLU.0b013e318262ad9b.

ncbi.nlm.nih.gov|Par Donta ST , et al.