Babesiosis was once only seen in animals, especially cattle, when it was called Red water fever. Humans were once able to fight it off easily, unless they had AIDS or had had their spleen removed
Now it's another tick borne disease which is not properly tested for, and which could be an undiagnosed factor in patients sick after tick bites.
Babesiosis-Induced Acute Kidney Injury With Prominent Urinary Macrophages.
Luciano RL, Moeckel G, Palmer M, Perazella MA.
American Journey of Kidney Diseases, online before print, 2013 May 2,
pii: S0272-6386(13)00674-4.
http://dx.doi.org/10.1053/j.ajkd.2013.02.376
Abstract
Babesia is an obligate intracellular erythrocyte parasite
that can infect humans. Severe symptomatic disease from
massive hemolysis and multiorgan system failure, including
acute kidney injury (AKI), occurs. Acute tubular injury from
a combination of volume depletion and heme pigment toxicity
from profound hemolysis is the most common cause of AKI.
We present a case of severe babesiosis complicated by
dialysis-requiring AKI with the unique finding of large
macrophages containing engulfed erythrocyte fragments in
urine sediment. This urinary finding raised the possibility
of another diagnosis distinct from acute tubular injury.
Subsequent kidney biopsy demonstrated infection-associated
acute interstitial nephritis.