Researchers discover new pathway of toxic proteins (wastes) that are characteristic of neurodegenerative diseases.
"Many neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's disease are associated with the accumulation of abnormal proteins and clumped. Cellular "garbage" of this kind can be eliminated in cellular recycling stations - the so-called lysosomes. Scientists at the Max Planck Institute for Biochemistry in Martinsried near Munich have now discovered a new family of helper proteins that detect labeled protein waste and escort to the lysosomes, where it is then broken down and recycled. The results of the study, now in the journal Cell published, are critical to understanding how cells dispose of their toxic waste and will open up new ways to combat neurodegenerative diseases."
(To read more linked below, please use an online translator if you're not fluent in German.)
"Many neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's disease are associated with the accumulation of abnormal proteins and clumped. Cellular "garbage" of this kind can be eliminated in cellular recycling stations - the so-called lysosomes. Scientists at the Max Planck Institute for Biochemistry in Martinsried near Munich have now discovered a new family of helper proteins that detect labeled protein waste and escort to the lysosomes, where it is then broken down and recycled. The results of the study, now in the journal Cell published, are critical to understanding how cells dispose of their toxic waste and will open up new ways to combat neurodegenerative diseases."
(To read more linked below, please use an online translator if you're not fluent in German.)
