A British paper from 1988.
Barts, Charing Cross, and Southampton doctors came to the conclusion that Lyme was persistent.
Journal of Neurology, Neurosurgery, and Psychiatry 1988;51:699-703
The neurological complications of Borrelia burgdorferi
in the New Forest area of Hampshire.
D E Bateman, N F Lawton, J E White, R J Greenwood, D J M Wright
From the Wessex Neurological Centre and Department of Dermatology, Southampton General Hospital,
Department of Neurological Sciences, St Bartholomew's Hospital, and Department of Microbiology, Charing Cross,: Hospital, London, UK
http://europepmc.org/articles/
<The pathogenesis of the neurological complications is uncertain. It has been suggested that they are immunological rather than due to the continued presence of the organism. However, the organism has been cultured from the CSF and there is good evidence that the meningeal features of the disease respond to parenteral penicillin. Also similar clinical features are seen in the course of other infections, for example tuberculous meningitis, which are known to be due to the presence of the organism.
Although peripheral nerve involvement does occur in B. burgdorferi infection, this is generally mild in contrast to the severity of the radiculopathy. This is well illustrated by patient 4 whose nerve conduction studies showed mild distal slowing but considerable prolongation of the F wave latencies in keeping with the
severe radiculopathy. These peripheral abnormalities may well be immunologically mediated but it seems likely that the common neurological manifestations of B. burgdorferi infection (Bannwarth's syndrome and a chronic meningitis) are due to the presence of
the organism.
Full paper here:
http://europepmc.org/articles/
