Lyme Disease May Be Diagnosable via Transcriptome Signature

Researchers describe genes that may serve as biomarkers for the diagnosis of Lyme disease. This study is the first to document changes in gene expression due to Lyme infection, and might radically change how we diagnose Lyme.
The study examined 29 patients before and after they received a three-week course of antibiotic treatment and also six months later. Compared to patients with other active bacterial or viral infections, the Lyme disease patients had distinctive gene signature ....

Gene expression signature of Lyme disease could inform new diagnostic approaches and reveal new therapeutic targets.