Here's another article that once again highlights the desperate need for further research: "For many people, though, the clinical situation is far more complicated. Some who have been infected with borrelia don’t notice the rash. Others—up to a quarter of those with Lyme, including Kaleigh Ahern—never even get one. Most troubling, some patients who are treated continue to suffer from a variety of symptoms long after their therapy has ended. Nobody really knows why they fail to get better.”
"Why patients fail to get better and how scientists can help them is an open question, Specter writes, though patients say the first step toward winning the war on Lyme is awareness."
http://www.weather.com/health/when-lyme-disease-cant-be-cured-20130625