Before diagnose a patient with ALS, a doctor must verify the following infections: tetanus and bacteria which determine Lyme Borreliosis and viral infections

For patients who have been diagnosed with ALS:

In the Harrison’s Manual of Medicine, 15th Edition, on the acute conditions of the neuron motor it can be found: poliomyelitis, herpes zoster and Coxackie viruses.

Before diagnose a patient with ALS, a doctor must verify the following infections: tetanus and bacteria which determine Lyme Borreliosis and viral infections (as those mentioned above).

It is also necessary to investigate: poisoning with heavy metals and other sources: electric shocks and radiations X and other medications.

Diagnosis is complex and differential one includes: urinary and blood screening for heavy metals, thyroid functions, immunoelectrophoresis, correlations between lysosomal enzymes, anti-GM1 antibody, B12 levels, VDRL, Hemogram, VSH, serum biochemistry analysis.

Coxackie virus – it belongs to Enterovirus genus and it is split in two groups- Coxackie A and Coxackie B.

Group A Coxackie can determinate Herpangina
Coxackie A10 produces Pharyngitis
Coxackie A16 produces HFMD-( Hand-foot-moth- disease)
Coxackie A24 causes Acute hemorrhagic conjunctivitis

Coxackie Group B cause epidemic pleurodynia, myocarditis and pericarditis.
Both -- Coxackie A and Coxackie B Gropus can cause aseptic meningitis and rashes.

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