collecte section Bourgogne

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CDC researchers report that Lyme disease bacteria, Borrelia burgdorferi, appear to use proteins to bind to aggrecan and destroy its functio


Aggrecan is a protein that is crucial to cartilage structure and the function of joints. Now, CDC researchers report that Lyme disease bacteria, Borrelia burgdorferi, appear to use proteins to bind to aggrecan and destroy its function which "may provide the organism with the capability to colonize connective tissues." They suggest that this "may contribute to the pathogenesis of Lyme arthritis." 

The new paper appears in the current issue of Molecular Microbiology: http://onlinelibrary.wiley.com/doi/10.1111/mmi.12276/abstract













Aggrecan is a protein that is crucial to cartilage structure and the function of joints. Now, CDC researchers report that Lyme disease bacteria, Borrelia burgdorferi, appear to use proteins to bind to aggrecan and destroy its function which "may provide the organism with the capability to colonize connective tissues." They suggest that this "may contribute to the pathogenesis of Lyme arthritis." The new paper appears in the current issue of Molecular Microbiology: http://onlinelibrary.wiley.com/doi/10.1111/mmi.12276/abstract
Aggrecan is a protein that is crucial to cartilage structure and the function of joints. Now, CDC researchers report that Lyme disease bacteria, Borrelia burgdorferi, appear to use proteins to bind to aggrecan and destroy its function which "may provide the organism with the capability to colonize connective tissues." They suggest that this "may contribute to the pathogenesis of Lyme arthritis."

The new paper appears in the current issue of Molecular Microbiology: http://onlinelibrary.wiley.com/doi/10.1111/mmi.12276/abstract